What is a potential consequence of aspirin use in people with active gastrointestinal bleeding?

Aspirin has antiplatelet properties, meaning that it inhibits the aggregation of platelets in the blood. In individuals with active gastrointestinal bleeding, the use of aspirin can exacerbate this condition. By preventing platelet clumping, aspirin hinders the body’s natural response to stop bleeding; therefore, it can lead to more significant or prolonged bleeding episodes. This risk is particularly concerning in the gastrointestinal tract, where the presence of bleeding ulcers or lesions may worsen if aspirin is administered.

In cases of active bleeding, the body's normal mechanisms to form clots and control bleeding may be impaired, and the anticoagulant effect of aspirin can further complicate the situation, potentially causing severe health risks.